《生物信息學》是該領域的領先期刊，出版學術和工業研究人員感興趣的高質量科學論文和評論文章。其主要研究方向是基因組生物信息學和計算生物學的新進展。期刊中有兩個截然不同的部分——發現筆記和應用筆記——側重于篇幅較短的論文;前者使用計算方法報告生物學上有趣的發現，后者探索用于實驗的應用。

The leading journal in its field, Bioinformatics publishes the highest quality scientific papers and review articles of interest to academic and industrial researchers. Its main focus is on new developments in genome bioinformatics and computational biology. Two distinct sections within the journal - Discovery Notes and Application Notes - focus on shorter papers; the former reporting biologically interesting discoveries using computational methods, the latter exploring the applications used for experiments.