《化學-生物相互作用》發表研究報告和評論文章，檢查分子、細胞和/或毒理學相關結果的生化基礎。特別強調與化學品和生物系統之間的相互作用有關的機制。結果可能包括體內和體外合成或自然產生的化學物質引起的所有傳統終點。感興趣的終點包括但不限于致癌、誘變、呼吸毒理學、神經毒理學、生殖和發育毒理學以及免疫毒理學。

Chemico-Biological Interactions publishes research reports and review articles that examine the molecular, cellular, and/or biochemical basis of toxicologically relevant outcomes. Special emphasis is placed on mechanisms associated with interactions between chemicals and biological systems. Outcomes may include all traditional endpoints caused by synthetic or naturally occurring chemicals, both in vivo and in vitro. Endpoints of interest include, but are not limited to, carcinogenesis, mutagenesis, respiratory toxicology, neurotoxicology, reproductive and developmental toxicology, and immunotoxicology.