《化學與生物學》雜志在化學與生物學交界的所有領域發表新研究報告。《化學與生物學》強烈鼓勵提交使用化學工具對生物功能和機制提供獨特見解的文章。闡明生物過程基本化學性質的研究也將受到好評。其他化學家和生物學家感興趣的相關研究也將被考慮。一般來說，要想被認為適合在本刊發表，主要以遺傳學、計算學或理論為重點的研究必須包含確鑿的實驗數據。所有的文章不僅應該對當前的領域有重要意義，而且應該對來自廣泛的化學-生物學社區的不同讀者有興趣。

Chemistry & Biology publishes reports of novel investigations in all areas at the interface of chemistry and biology. Chemistry & Biology strongly encourages submission of articles in which chemical tools are used to provide unique insight into biological function and mechanism. Studies that illustrate the underlying chemistry of biological processes will also be viewed favorably. Other relevant studies of interest to chemists and biologists will also be considered. In general, to be considered suitable for publication in this journal, investigations that primarily have a genetic, computational, or theoretical focus must contain substantiating experimental data. All articles should not only be of significance to the immediate field but should also be of interest to our diverse readership from the broad chemical-biology community.