臨床神經生理學雜志的特點是原創的研究文章，涵蓋了腦電圖和誘發電位，臨床神經學，神經外科，精神病學和中樞神經系統的實驗研究的關鍵問題。每一期的一半都是對腦電圖專家感興趣的主題的專題評論。這個流行的特性使編輯人員能夠深入探索新的或有爭議的發現。此外還包括來自美國臨床神經生理學協會的實踐指南，摘要，書評，社論，以及來自美國腦電圖協會和美國資格委員會的新聞和公告。

The Journal of Clinical Neurophysiology features original research articles that cover key concerns in electroencephalography and evoked potentials, clinical neurology, neurosurgery, psychiatry, and experimental research on the central nervous system. Half of each issue is devoted to topical reviews on a subject of interest to EEG specialists. This popular feature enables the editors to explore new or controversial findings in depth. Also included are practice guidelines from the American Clinical Neurophysiology Society, abstracts, book reviews, editorials, and news and announcements from the Society and the American Board of Qualification in Electroencephalography.