目前，該權威期刊每年出版24期，嚴格引用環境毒理學領域的原始研究成果，包括目標器官毒性、免疫毒理學、風險評估、致癌、誘變、生態毒理學、影響健康的環境因素、水生毒理學等。重點是自然和人為環境污染物的毒理學效應及其對完整生物體和體外系統的作用。目前正更多地注意對暴露人口中選定的工人群體進行流行病學研究的結果。為了促進短文章的及時出版，該期刊增加了一個新的快速通訊板塊，讓讀者隨時掌握該領域的重要新進展。同時發表了當前毒理學研究領域的評論。

Now published twenty-four times per year, this authoritative journal features strictly refereed original research in the field of environmental toxicology in general as well as in special interest fields such as target organ toxicities, immunotoxicology, risk assessment, carcinogenesis, mutagenesis, ecotoxicology, environmental factors affecting health, and aquatic toxicology. Emphasis is on the toxicological effects of natural and anthropogenic environmental pollutants and their action on both intact organisms and in vitro systems. Increased attention is being placed on the results of epidemiological studies of select groups of workers in exposed populations. To facilitate the timely publication of short articles, the journal has added a new Rapid Communications section, keeping readers on top of important new developments in the field, as they happen. Also published are refereed critical reviews in scientific areas of current toxicological interest.