異種生物包括三個主要領域：一般異種生物化學，包括動物、植物和微生物中藥物和環境化學物質的代謝和處置以及相關方法學；分子毒理學，關于毒性機制和分子水平毒理學研究；臨床藥代動力學ND代謝，主要研究外源化合物在人體內的藥動學行為。異種生物與國際異種生物研究學會之間建立了密切聯系，引起了該雜志的專題報道。

Xenobiotica covers three main areas: general xenobiochemistry, including the metabolism and disposition of drugs and environmental chemicals in animals, plants and micro-organisms, and the related methodology; molecular toxicology, concerning mechanisms of toxicity and the study of toxicology at the molecular level; and clinical pharmacokinetics and metabolism, focusing on the pharmacokinetic behavior of foreign compounds in man. A close liaison between Xenobiotica and the International Society for the Study of Xenobiotics has been established, giving rise to special issues of the journal.