自然結構與分子生物學是一個結構與分子研究的綜合論壇。該雜志強調功能和機械的理解如何分子組成在一個生物過程中協同工作。結構性數據或許能提供這樣的洞見，但它們不是發表在《華爾街日報》上的先決條件。感興趣的具體領域包括但不限于:蛋白質、核酸等大分子的結構和功能多組分配合物的結構與功能DNA復制，修復和重組染色質結構和重塑轉錄RNA加工翻譯轉錄和翻譯的調節非編碼rna的功能蛋白質折疊、加工和降解蛋白質和RNA的分類和運輸信號轉導和細胞內信號轉導膜過程細胞表面蛋白和細胞間的相互作用疾病的分子基礎

Nature Structural & Molecular Biology is an integrated forum for structural and molecular studies. The journal places a strong emphasis on functional and mechanistic understanding of how molecular components in a biological process work together. Structural data may provide such insights, but they are not a pre-requisite for publication in the journal.Specific areas of interest include, but are not limited to:Structure and function of proteins, nucleic acids and other macromoleculesStructure and function of multi-component complexesDNA replication, repair and recombinationChromatin structure and remodelingTranscriptionRNA processingTranslationRegulation of transcription and translationFunctions of noncoding RNAsProtein folding, processing and degradationSorting and trafficking of proteins and RNASignal transduction and intracellular signalingMembrane processesCell surface proteins and cell-cell interactionsMolecular basis of disease