《癌癥免疫學研究》發表了杰出的原創文章，報道了癌癥免疫學的重大進展，涵蓋了從宿主-腫瘤相互作用的基礎研究到模型系統中的發育療法、患者的早期轉化研究和晚期臨床試驗。該雜志向癌癥研究領域傳播免疫學知識，促進跨學科工作，從而加深對宿主-腫瘤關系、更有效的癌癥治療和改善臨床結果的理解。論文被嚴格審查，具體的主題包括內源性抗腫瘤免疫，腫瘤促進炎癥，癌癥抗原，疫苗，抗體，細胞治療，細胞因子，免疫調節，免疫抑制，癌癥治療的免疫調節作用，新興技術，和臨床研究。該雜志的特色包括“免疫學碩士”-由領先的免疫學家引物-和“癌癥免疫學在十字路口”-的觀點，強調免疫學與其他領域的癌癥研究和相關學科的交叉。

Cancer Immunology Research publishes outstanding original articles reporting major advances in cancer immunology that span the discipline from basic investigations in host-tumor interactions to developmental therapeutics in model systems, early translational studies in patients, and late-stage clinical trials. The journal disseminates knowledge of immunology to the cancer research community, catalyzing cross-disciplinary work that yields a deeper understanding of the host-tumor relationship, more potent cancer treatments, and improved clinical outcomes.Papers are stringently reviewed, and specific topics of interest include endogenous antitumor immunity, tumor-promoting inflammation, cancer antigens, vaccines, antibodies, cellular therapy, cytokines, immune regulation, immune suppression, immunomodulatory effects of cancer treatment, emerging technologies, and clinical investigations. The journal's special features include "Masters of Immunology"—primers by leading immunologists—and "Cancer Immunology at the Crossroads"—perspectives that highlight the intersection of immunology with other areas of cancer research and allied disciplines.