美國化學學會中心科學出版了關于化學和相關領域研究的最引人注目、最重要的初步報告，其中化學方法起著關鍵作用。它也是美國化學學會出版的第一本完全開放的期刊。“中心科學”一詞在近40年前被廣泛使用，經常用來描述化學在連接物理和生命科學以及基礎科學與醫學和工程等應用學科方面的重要作用。《美國化學學會中心科學》是一本多學科期刊，旨在向廣泛的化學和科學界發表具有卓越質量和興趣的文章。該雜志論述了化學基礎領域的重要進展，以及應用和跨學科研究，強調了化學在其他許多科學學科中的重要作用。編輯們預計每年發表不超過200篇文章，對被認為具有卓越科學品質、獨創性、重要性和全球化學界興趣廣泛的文章給予額外的重視。新的期刊文章一準備好發表就出現在網上，期刊每月出版在線期刊。ACS中心科學是完全開放的，沒有訂閱費或作者的文章出版費。審查過程嚴格有效。該期刊出版了各種各樣的評論、采訪和評論材料。

ACS Central Science publishes the most compelling, important primary reports on research in chemistry and in allied fields, wherein chemical approaches play a key role. It is also the first fully open access journal published by the American Chemical Society.Popularized almost 40 years ago, the term "central science" is frequently used to describe chemistry''s focal role in bridging the physical and life sciences, and the basic sciences with applied disciplines such as medicine and engineering.ACS Central Science is a multidisciplinary journal that aims to publish articles of exceptional quality and interest to the broad chemistry and scientific community. The journal addresses important advances in fundamental areas of chemistry, as well as applied and interdisciplinary research highlighting the seminal role of chemistry in a wide range of other scientific disciplines.The Editors anticipate publishing no more than 200 articles per year, placing a premium on articles deemed to be of exceptional scientific quality, originality, significance, and breadth of interest to the global chemistry community. New journal articles appear online as soon as they are ready for publication, and the journal publishes online monthly issues.ACS Central Science is entirely open access, with no subscription fees or article publishing charges for authors. The review process is stringent and efficient. The journal publishes a diverse selection of reviews, interviews and commentary material.